Delay treatment whilst you are well
Not been on site recently as trying to get my head around what is happening.
KRAS wild type with BRAF mutation so unsuitable for treatment with either Cetuximab or Panitumunab (eGFR inhibitors).
I asked about MSS/MSI and oncologist said MSI testing has not been performed because there is no licensed drug available for MSI high tumours in UK.
Do not have Lynch Syndrome.
From latest CT scan have two mets in lung, largest was 5mm in August, 20mm in November and 21mm in January. No visible change to thoracic and mesenteric lymphadenopathy and suspicious liver lesion remains the same. Surgery not an option due to mets in lymphatic system.
As having no real symptoms at the moment and mets appear slow growing I am not on any treatment as oncologist wants to wait until either I don’t feel as well or he detects a problem arising from CT scans and bloods. My next CT scan is scheduled for mid-April. Plan is to treat with Irinotecan with 5FU folinic which only has a 20% chance of working due to number of possible sites. Mitomycin has also been mentioned as a possible treatment.
I sort of get all this and have questioned the wait but It was explained that this is what palliative treatment is. I am 65 years old and very active, is this normal practice? Any comments gratefully received as this site is so knowledgeable and supportive. Thank you for reading my missive.